20.500.12556/ReVIS-11833 Potenciali za uporabo konoplje pri demenci pregled literature diplomsko delo visokošolskega strokovnega študijskega programa prve bolonjske stopnje Zdravstvena nega TEORETIČNA IZHODIŠČA: Demenca je ena najpogostejših nevrodegenerativnih bolezni v starosti, ki močno vpliva na kakovost življenja obolelih. Farmakološko zdravljenje pogosto ne zadostuje pri lajšanju simptomov, zato narašča zanimanje za alternativne pristope. Raziskovanje terapevtskega potenciala konoplje se je razširilo tudi na področje demence. Zato smo želeli raziskati njen potencial pri obvladovanju simptomov in stališča ter znanja zdravstvenih delavcev glede njene uporabe. METODE: Izvedli smo kakovosten pregled literature in raziskav preko baz COBISS, PubMed, ResearchGate in Google Učenjak. Uporabili smo diagram PRISMA za izbiro relevantnih virov ter prilagojeno lestvico PEDro za oceno kakovosti izbranih študij. REZULTATI: Ugotovili smo, da na temo potencialov konoplje pri demenci obstaja veliko znanstvenih člankov, vendar pa je le malo izvedenih relevantnih in strokovnih študij. To nakazuje na omejitve, povezane s pomanjkanjem reprezentativnih vzorcev in nezadostnim številom kliničnih raziskav. V pregledu je bilo najdenih 16 relevantnih študij, ki so bile tudi ocenjene z lestvico PEDro. Rezultati raziskav kažejo, da kanabinoidi, zlasti THC in CBD, kažejo potencial pri zmanjšanju nevropsihiatričnih simptomov. Prav tako je ugotovljeno, da je raven znanja in stališč medicinskih sester o uporabi konoplje v zdravstveni praksi pomanjkljiva. RAZPRAVA: Povprečna metodološka ocena študij je 4 od 5 točk, kar kaže na zadovoljivo metodološko kakovost. Ugotovljeno je, da uporaba kanabinoidov v medicini potrebuje dodatne raziskave, da bi se lahko uveljavila kot standardna terapija za demenco. Nadaljnje raziskave bi morale vključevati večje število pacientov, raznolikost populacij in dolgoročno spremljanje. Prav tako je ugotovljeno, da je pomemben razvoj izobraževalnih programov za zdravstvene delavce, tako bi se izboljšalo razumevanje terapevtske uporabe konoplje. THEORETICAL BACKGROUND: Dementia is one of the most common neurodegenerative diseases in old age, significantly affecting the quality of life of those affected. Pharmacological treatment often proves insufficient in alleviating symptoms, leading to a growing interest in alternative approaches. Recently, research into the therapeutic potential of cannabis has also expanded into the field of dementia. Therefore, we aimed to investigate the therapeutic potential of cannabis in managing dementia symptoms. We also explored the attitude and level of knowledge of healthcare professionals regarding the use of cannabis in nursing care. METHODS: We conducted a comprehensive review of literature and research using databases such as COBISS, PubMed, ResearchGate and Google Scholar. The PRISMA diagram was used for selecting relevant sources and an adapted PEDro scale was applied to assess the methodological quality of the chosen studies. RESULTS: We found that there is a significant amount of scientific articles on the potentials of cannabis in dementia; however, there are very few relevant and professional studies conducted. This indicates limitations related to a lack of representative sample and an insufficient number of clinical studies. The review identified 16 relevant studies, which were also assessed using PEDro scale. The results of the research indicates that cannabinoids, particularly THC and CBD, show potential in reducing and attitudes of nurses regarding the use of cannabis in healthcare practice in lacking. DISCUSSION: The average methodological rating of the studies id 4 out of 5 points, indicating satisfactory methodological quality. It has been determined that the use of cannabinoids in medicine still requires further research before it can be established as a standard therapy for dementia. Future research should include a larger number of patients, diversity of populations, and long-term monitoring. Additionally, the development of educational programs for healthcare professionals is crucial to improve understanding of the therapeutic use of cannabis. medicinska uporaba konoplje endokanabinoidni sistem konoplja in demenca vpliv konoplje na demenco medicinske sestre in konoplja medical use of cannabis endocannabinoid system cannabis and dementia influence of cannabis on dementia nurses and cannabis true false false B. Sandra Slovenski jezik Angleški jezik Diplomsko delo/naloga 2025-06-23 14:15:09 2025-06-23 14:15:09 2025-06-24 03:05:07 0000-00-00 00:00:00 2024 0 Maribor 2024 Maribor 43 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.892.3(043.2) 240135171 DIP_Bezjak_Sandra_2024.pdf DIP_Bezjak_Sandra_2024.pdf 1 0D46DB0A70152391FBB5DF2A71AA06A5 6bd53d63202c610dca1195c4efaeccc9e976931853598b02ade47b0ed86b1833 bd3885ec-502b-11f0-8080-001a4af901a5 https://revis.openscience.si/Dokument.php?lang=slv&id=13684 Univerza Alma Mater Europaea 0 0 0