20.500.12556/ReVIS-13233 Diagnosticiranje celiakije pri odraslem: specifični simptomi, diagnostične metode in vpliv na kakovost življenja diplomsko delo visokošolskega strokovnega študijskega programa prve bolonjske stopnje Zdravstvena nega Uvod: Celiakija je kronična avtoimunska bolezen, ki se pojavi pri genetsko dovzetnih posameznikih po zaužitju glutena – beljakovine, prisotne v pšenici, ječmenu in rži. Imunski odziv povzroči poškodbe sluznice tankega črevesa, kar vodi v moteno absorpcijo hranil in številne zdravstvene zaplete. Zaradi raznolikih in pogosto nespecifičnih simptomov je diagnoza pogosto postavljena z zamudo, kar negativno vpliva na kakovost življenja bolnikov. Metode dela: V empiričnem delu je bila uporabljena kvantitativna metoda zbiranja podatkov z anketnim vprašalnikom, ki ga je izpolnilo 171 odraslih oseb s potrjeno diagnozo celiakije v Sloveniji. Cilj raziskave je bil proučiti simptome pred postavitvijo diagnoze, vpliv bolezni na vsakdanje življenje in stopnjo ozaveščenosti o bolezni v družbi. Rezultati: Analiza podatkov je pokazala, da so bili med najpogostejšimi simptomi pred diagnozo napihnjenost (74 %), bolečine v trebuhu (66 %) in driska (53 %). Večina anketirancev je bila diagnosticirana pri gastroenterologu. Bolezen pomembno vpliva na kakovost življenja, zlasti pri prehranjevanju zunaj doma, potovanjih in psihosocialnem funkcioniranju. Večina sodelujočih ocenjuje, da je splošna ozaveščenost javnosti o celiakiji nezadostna. Razprava in zaključek: Ugotovitve potrjujejo, da zaradi nespecifičnih simptomov pogosto prihaja do zamude pri diagnosticiranju celiakije. Rezultati poudarjajo potrebo po boljši prepoznavi simptomov s strani zdravstvenih delavcev, večji ozaveščenosti v javnosti in boljši sistemski podpori bolnikom za izboljšanje njihovega vsakdanjega ter psihosocialnega funkcioniranja. Introduction: Celiac disease is a chronic autoimmune disorder that occurs in genetically predisposed individuals upon the ingestion of gluten, a protein found in wheat, barley, and rye. The immune response damages the lining of the small intestine, leading to impaired nutrient absorption and various health complications. Due to the wide range of both gastrointestinal and extraintestinal symptoms, diagnosis is often delayed, which negatively affects patients’ quality of life. Methods: The empirical part of the thesis was based on a quantitative research method using a structured questionnaire, completed by 171 adults with a confirmed diagnosis of celiac disease in Slovenia. The research aimed to examine the prevalence of symptoms prior to diagnosis, the impact of the disease on daily life, and the level of public awareness. Results: The most commonly reported symptoms before diagnosis were bloating (74%), abdominal pain (66%), and diarrhea (53%). Most participants were diagnosed by a gastroenterologist. Celiac disease significantly affects quality of life, especially in terms of eating outside the home, traveling, and psychosocial functioning. The majority of respondents believe that public awareness of the disease is poor. Discussion: The findings confirm that due to non-specific symptoms, there is often a delay in diagnosing celiac disease. The study highlights the need for earlier recognition of symptoms by healthcare professionals, greater public awareness, and stronger systemic support for patients to improve their daily and psychosocial well-being. celiakija diagnoza brezglutenska dieta kakovost življenja odrasli bolniki osveščenost celiac disease diagnosis gluten-free diet quality of life adult patients awareness true false false A. Topler Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-02-26 09:48:42 2026-02-26 09:48:43 2026-02-27 03:10:27 0000-00-00 00:00:00 2025 0 Maribor 2025 Maribor 37 str., [28] str. pril. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.341-008.6-053.8(043.2) 269716227 https://d.cobiss.net/repository/si/files/269716227/173711/Topler_Aleksandra_dd_2025.pdf 1 f4f2f7fb-12ef-11f1-9cb0-001a4af901a5 https://revis.openscience.si/Dokument.php?lang=slv&id=15715 Topler_Aleksandra_dd_2025.pdf Topler_Aleksandra_dd_2025.pdf 1 5139E14803366BB1D26D71849DEC9E12 1332deb9d30de9084c273ea68912e15b30701810e86a8f1bd5d7b58308359bf2 f9be70dc-12ef-11f1-9cb0-001a4af901a5 https://revis.openscience.si/Dokument.php?lang=slv&id=15716 Univerza Alma Mater Europaea 0 0 0